Study associates Alzheimer’s risk with banned pesticide DDT

January 28, 2014
daddaughterkidUSA Today (1/28, Szabo) reports that a study published online Jan. 27 in JAMA Neurology associates “exposure to the insecticide” dichlorodiphenyltrichloroethane (DDT) “with Alzheimer’s disease.”

Bloomberg News (1/28, Ostrow) reports that “researchers analyzed blood samples of 86 people who had been diagnosed with Alzheimer’s and 79 patients without the condition.” In addition, they examined tissue and blood samples from 11 deceased Alzheimer’s patients. The investigators found that “people with Alzheimer’s disease had about four times the level of” dichlorodiphenyldichloroethylene (DDE), “a DDT byproduct in their blood, compared with those who didn’t have” Alzheimer’s.
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Surgeon general links smoking to several illnesses

January 17, 2014
The Washington Post (1/16, Dennis) reports that, in “another round of evidence of tobacco’s potential to harm nearly every human organ,” Acting Surgeon General Boris D. Lushniak found in a new report released Friday that “smoking is a cause of liver cancer and colorectal cancer,” as well as “type 2 diabetes mellitus, age-related macular degeneration, erectile dysfunction and rheumatoid arthritis.” He also said “it can impair the immune system, worsen asthma and cause cleft lips and palates in fetuses,” while second-hand smoke exposure can cause strokes. The American Academy of Pediatrics and the American Heart Association, along with other public health and anti-tobacco groups, last week “called for a ‘new national commitment’ to eliminating tobacco-related deaths.” They suggested increasing tobacco taxes, more smoke-free workplace laws, stricter FDA oversight of tobacco, “and aggressive advertising campaigns to help smokers quit and keep nonsmokers from lighting up.”

USA Today (1/17, Szabo) writes that the report found “smoking causes even more physical and financial damage than previously estimated,” including 480,000 Americans dying each year and the lost of almost $286 billion a year in medical costs and lost productivity due to premature deaths. This is also the first time the surgeon general concluded smoking is “causally linked” to diabetes, colorectal cancer, and liver cancer. Thomas Frieden, director of the Centers for Disease Control and Prevention, said, “Amazingly, smoking is even worse than we knew,” adding, “Even after 50 years, we’re still finding new ways that smoking maims and kills people.”
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Study: FDA’s medicine approval process lacks uniformity

FDAJanuary 22, 2014The Washington Post (1/22, Dennis) reports the FDA’s certifications of medicines being “safe and effective” are based on widely varied data, citing an analysis by researchers at Yale University’s School of Medicine. Nicholas Downing, the lead author of the study, “which examined nearly 200 new drug approvals between 2005 and 2012,” said, “Not all FDA approvals are created equally.” For instance, the study says, the FDA required that many new medicines “prove themselves in large, high-quality clinical trials,” however, about a third received approval based on one clinical trial, while “many other trials involved small groups of patients and shorter durations.”

USA Today (1/21, Szabo) reports the study, published in a series of articles in the Journal of the American Medical Association, found that many heart devices “have been approved through” a FDA “process that assumes newer models are safe and effective based on the approval of earlier versions.” Devices such as implanted defibrillators undergo “rigorous review” when they receive initial approvals but subsequent changes, however, “are often made through a ‘supplemental’ review process that doesn’t necessarily require them to be tested in clinical trials in humans.”
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Higher alcohol consumption in middle-aged men tied to memory decline

January 16, 2014
liquor and memory declineOne national news broadcast, several major newspapers, one wire source, and numerous consumer online medical sources report a study suggesting that mental decline is associated with heavy drinking in middle-aged men.

ABC World News (1/15, story 8, 1:40, Sawyer) reported that a study (1/16) published online Jan. 15 in the journal Neurology “shows that beer and wine speeds up memory loss, but it seems only if you drink a certain amount.”

The Los Angeles Times (1/15, Healy) reports, “Middle-aged men who consume an average of more than 2½ alcoholic drinks per day accelerate the rate at which their memories decline by almost six years over a 10-year span,” the study found. What’s more, “while a higher consumption of spirits such as vodka, gin, whiskey or scotch was linked to the fastest rates of mental decline in men, researchers saw little difference between the cognitive loss seen in heavy beer drinkers (who drank more than 2½ 12-ounce beers per day) and that seen in men who quaffed a half-bottle of wine or more per day.”
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